Vòng 18
| TT | Đội | Trận | Thắng | Hòa | Bại | HS | Điểm |
|---|---|---|---|---|---|---|---|
| 1 |
 Philadelphia Union
|
17 | 10 | 4 | 3 | 14 | 34 |
| 2 |
 Vancouver Whitecaps
|
15 | 9 | 5 | 1 | 15 | 32 |
| 3 |
 FC Cincinnati
|
17 | 9 | 3 | 5 | 1 | 30 |
| 4 |
 San Diego FC
|
17 | 9 | 3 | 5 | 11 | 30 |
| 5 |
 Inter Miami CF
|
16 | 8 | 5 | 3 | 9 | 29 |
| 6 |
 Minnesota United FC
|
17 | 8 | 6 | 3 | 10 | 30 |
| 7 |
 Portland Timbers
|
16 | 7 | 5 | 4 | 3 | 26 |
| 8 |
 Nashville
|
17 | 8 | 5 | 4 | 9 | 29 |
| 9 |
 Columbus Crew
|
17 | 7 | 7 | 3 | 3 | 28 |
| 10 |
 Seattle Sounders
|
17 | 7 | 5 | 5 | 3 | 26 |
| 11 |
 New York Red Bulls
|
17 | 8 | 3 | 6 | 9 | 27 |
| 12 |
 Los Angeles FC
|
15 | 6 | 5 | 4 | 5 | 23 |
| 13 |
 Orlando City
|
17 | 7 | 6 | 4 | 9 | 27 |
| 14 |
 San Jose Earthquakes
|
17 | 6 | 4 | 7 | 6 | 22 |
| 15 |
 Colorado Rapids
|
16 | 6 | 4 | 6 | -4 | 22 |
| 16 |
 Charlotte FC
|
17 | 8 | 1 | 8 | 1 | 25 |
| 17 |
 Houston Dynamo
|
17 | 5 | 5 | 7 | -3 | 20 |
| 18 |
 New York City FC
|
17 | 7 | 4 | 6 | 0 | 25 |
| 19 |
 New England Revolution
|
15 | 6 | 5 | 4 | 5 | 23 |
| 20 |
 Austin FC
|
17 | 5 | 5 | 7 | -9 | 20 |
| 21 |
 Chicago Fire
|
15 | 6 | 4 | 5 | 0 | 22 |
| 22 |
 FC Dallas
|
16 | 4 | 6 | 6 | -8 | 18 |
| 23 |
 DC United
|
17 | 4 | 6 | 7 | -13 | 18 |
| 24 |
 Sporting Kansas City
|
16 | 4 | 4 | 8 | -3 | 16 |
| 25 |
 Real Salt Lake
|
17 | 4 | 3 | 10 | -9 | 15 |
| 26 |
 Atlanta United
|
17 | 4 | 5 | 8 | -9 | 17 |
| 27 |
 Toronto FC
|
17 | 3 | 4 | 10 | -6 | 13 |
| 28 |
 St. Louis City
|
16 | 3 | 5 | 8 | -8 | 14 |
| 29 |
 Los Angeles Galaxy
|
17 | 1 | 4 | 12 | -21 | 7 |
| 30 |
 Montreal Impact
|
17 | 1 | 5 | 11 | -20 | 8 |