Vòng 25
| TT | Đội | Trận | Thắng | Hòa | Bại | HS | Điểm |
|---|---|---|---|---|---|---|---|
| 1 |
 FC Cincinnati
|
24 | 15 | 3 | 6 | 8 | 48 |
| 2 |
 San Diego FC
|
24 | 13 | 4 | 7 | 15 | 43 |
| 3 |
 Nashville
|
24 | 14 | 5 | 5 | 17 | 47 |
| 4 |
 Vancouver Whitecaps
|
23 | 12 | 6 | 5 | 13 | 42 |
| 5 |
 Philadelphia Union
|
24 | 14 | 5 | 5 | 17 | 47 |
| 6 |
 Minnesota United FC
|
24 | 11 | 8 | 5 | 13 | 41 |
| 7 |
 Seattle Sounders
|
23 | 10 | 7 | 6 | 4 | 37 |
| 8 |
 Columbus Crew
|
24 | 12 | 8 | 4 | 7 | 44 |
| 9 |
 Inter Miami CF
|
21 | 12 | 5 | 4 | 15 | 41 |
| 10 |
 Los Angeles FC
|
21 | 10 | 6 | 5 | 12 | 36 |
| 11 |
 Orlando City
|
24 | 10 | 8 | 6 | 11 | 38 |
| 12 |
 Portland Timbers
|
23 | 9 | 7 | 7 | 0 | 34 |
| 13 |
 Charlotte FC
|
24 | 11 | 2 | 11 | 2 | 35 |
| 14 |
 Colorado Rapids
|
24 | 8 | 6 | 10 | -6 | 30 |
| 15 |
 Austin FC
|
22 | 8 | 6 | 8 | -7 | 30 |
| 16 |
 New York City FC
|
23 | 10 | 5 | 8 | 4 | 35 |
| 17 |
 San Jose Earthquakes
|
24 | 7 | 8 | 9 | 4 | 29 |
| 18 |
 New York Red Bulls
|
24 | 9 | 6 | 9 | 4 | 33 |
| 19 |
 Chicago Fire
|
23 | 9 | 5 | 9 | 4 | 32 |
| 20 |
 Real Salt Lake
|
23 | 8 | 4 | 11 | -5 | 28 |
| 21 |
 New England Revolution
|
23 | 6 | 7 | 10 | -2 | 25 |
| 22 |
 Houston Dynamo
|
24 | 7 | 6 | 11 | -9 | 27 |
| 23 |
 Toronto FC
|
23 | 5 | 6 | 12 | -5 | 21 |
| 24 |
 FC Dallas
|
23 | 6 | 7 | 10 | -9 | 25 |
| 25 |
 Sporting Kansas City
|
23 | 6 | 6 | 11 | -6 | 24 |
| 26 |
 Atlanta United
|
23 | 4 | 8 | 11 | -16 | 20 |
| 27 |
 DC United
|
24 | 4 | 7 | 13 | -25 | 19 |
| 28 |
 St. Louis City
|
23 | 4 | 6 | 13 | -15 | 18 |
| 29 |
 Los Angeles Galaxy
|
24 | 3 | 7 | 14 | -20 | 16 |
| 30 |
 Montreal Impact
|
24 | 3 | 6 | 15 | -25 | 15 |